http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0828720-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba045776bcd32d32e3100da8dfce4e28 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-28 |
| filingDate | 1996-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6815f010ee7465053e8f58dc1b0640ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79bd23a9bd31ee4f3dce98bd7370cb90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3480fe539128c17f203bd0bce2051705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_add80a0c9542d05b42d8e92bc68363c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4770189f50f68627d4401bc7cc03ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce157a785107b5e5350b489303da588 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3117b8a16213c574e8effb2e3c2111bf |
| publicationDate | 1998-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0828720-A1 |
| titleOfInvention | Process for the preparation of substituted 5-hydroxy-oxazolidin-4-one |
| abstract | A process for the synthesis of a compound of general formula (II), wherein: R?2 and R3¿ are each independently hydrogen or C¿1?-C4 alkyl; A is an aromatic or heteroaromatic ring system optionally substituted with one or more substituents selected from: halogen or C1-C10 hydrocarbyl, -O(C1-C10 hydrocarbyl), -S(C1-C10 hydrocarbyl), -SO(C1-C10 hydrocarbyl) or -SO2(C1-C10 hydrocarbyl), cyano, nitro, SCN, SiR?c¿3 (where each Rc is independently C¿1?-C4 alkyl or phenyl), COR?7, CR7NOR8¿, NHOH, ONR7R8, SF5, COOR7, SO2NR?7R8, OR9 or NR10R11¿; and in which any ring nitrogen atom may be quaternised or oxidised; alternatively, any two substituents of the group A may combine to form a fused 5- or 6-membered saturated or partially saturated carbocyclic or heterocyclic ring in which any carbon or quaternised nitrogen atom may be substituted with any of the groups mentioned above for A or in which a ring carbon atom may be oxidised; R?7 and R8¿ are each independently hydrogen or C¿1?-C10 hydrocarbyl; R?9¿ is hydrogen, C¿1?-C10 hydrocarbyl, SO2(C1-C10 hydrocarbyl), CHO, CO(C1-C10 hydrocarbyl), COO(C1-C10 hydrocarbyl) or CONR?7R8; R10 and R11¿ are each independently hydrogen, C¿1?-C10 hydrocarbyl, O(C1-C10 hydrocarbyl), SO2(C1-C10 hydrocarbyl), CHO, CO(C1-C10 hydrocarbyl), COO(C1-C10 hydrocarbyl) or CONR?7R8¿; any of the hydrocarbyl groups within the group A may optionally be substituted with halogen (i.e. chlorine, bromine, fluorine or iodine), hydroxy, SO¿2NR?aRb (where R?a and Rb¿ are independently H or C¿1?-C6 alkyl), cyano, nitro, amino, mono- and dialkylamino in which the alkyl groups have from 1 to 6 or more carbon atoms, acylamino, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 alkylsulphinyl, C1-C6 alkylsulphonyl, carboxy, carboxyamide, in which the groups attached to the N atom may be hydrogen or lower hydrocarbyl optionally substituted with halogen; alkoxy carbonyl wherein the alkoxy group may have from 1 to 6 or more carbon atoms, or aryl such as phenyl; the process comprising cyclising a compound of general formula (VII); wherein A, R?2 and R3¿ are as defined for general formula (II), R20 is hydrogen, benzyl or benzyl substituted with up to five substituents selected from halo, C¿1?-C6 alkyl, O(C1-C6 alkyl) or nitro and R?21 is C¿1-C8 alkyl, benzyl or benzyl substituted with up to five of the substituents mentioned above for R20. |
| priorityDate | 1995-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 396.