abstract |
Prokayrotic FAB I polypeptides and DNA (RNA) encoding such FAB I and anprocedure for producing such polypeptides by recombinant techniques is disclosed. Alsondisclosed are methods for utilizing such FAB I for the treatment of infection, such as bacterialninfections. Antagonists against such FAB I and their use as a therapeutic to treat \infections,nsuch asstaphylococcal infections are also disclosed. Also disclosed are diagnostic assays forndetecting diseases related to the presence of FAB I nucleic acid sequences and the polypeptides inna host. Also disclosed are diagnostic assays for detecting polynucleotides encoding FAB I andnfor detecting the polypeptide in a host. |