| abstract |
Compounds of formula (II), wherein R1 is chlorine, fluorine or trifluoromethyl; R2 is hydrogen, chlorine, fluorine or trifluoromethyl; Z is CH or N; R3, R4 and R5, the same or different are hydrogen or C1-C4 alkyl, provided that R4 is different from R5 when R3 is hydrogen; X is O or S; R6 is a C1-C5 polyfluoroalkyl group containing at least two fluorine atoms and optionally other halogen atoms selected among chlorine and bromine; and their salts with pharmaceutically acceptable acids, are described. The compounds of formula (II) are endowed with antimycotic activity for human and veterinary use. |