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filingDate 1997-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2001-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25ba32eec0ba7172dac0b9ea462587c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bab48cc167d56b6b853eaaf77a36c59
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publicationDate 2001-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0818451-B1
titleOfInvention Process for the preparation of the enollactone of the 2-oxocyclohexylidene acetic acid and use for the preparation of the 2-coumaranone
abstract Preparation of 2-oxo cyclohexylidene acetic acid enol-lactone (I) comprises: (i) reacting glyoxylic acid with cyclohexanone in the presence of a halogenated acid to give a crude reaction product; and (ii) dissolving the above product in an organic solvent in the presence of a strong soluble acid or a strongly acidic resin. In (i), the acid is preferably HCl added in a 1-100% molar amount w.r.t. glyoxylic acid and the reagents are heated above 50 degrees C. The resulting crude product is dissolved in a solvent containing a benzene ring and treated with methane sulphonic acid or p-toluene sulphonic acid or with a strongly acidic sulphonic Amberlist (RTM) resin.
priorityDate 1996-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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