abstract |
The present invention is directed to amides ofnantibiotic A82846B (also known as chloroorienticin A), andnof N 4 -derivatives of A82846B. The present amide compoundsnare useful as antibacterials, especially for the control ofngram positive bacteria; the compounds are particularlynuseful for the control of resistant bacterial strains, suchnas vancomycin-resistant-enterococci ("VRE"). |