http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0816368-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0fd8ebc38f88e31cee884e938072023 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-2408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 1997-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10db4e557fc7547e284d6555b1a4e848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a98a409e6753203bc33b9b4ac0d6c23c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_981818b76ed942a4a08ed3b32d36f0f3 |
| publicationDate | 2003-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0816368-B1 |
| titleOfInvention | Chemical phoshorylation of oligonucleotides and reactants used therefor |
| abstract | Phosphoramidite building blocks according to the following formula 1 are used for phosphorylating oligonucleotides, preferably at the 5'- or 3'-terminus. The building blocks include phosphoramidite compounds according to formula 1: <CHEM> wherein DMTr is a 4,4'-dimethoxytrityl group; R1 is an electron withdrawing group; R2 is an electron withdrawing group which may be the same or different from the R1 group; R3 is an alkyl group; and R4 is an alkyl group which may be the same or different from the R3 group. Preferred electron withdrawing groups include -CO2Me groups, -CN groups, -CON(Me)2 groups, and -CONHMe groups, wherein Et represents an ethyl group and Me represents a methyl group. One preferred alkyl group is an isopropyl group. <IMAGE> |
| priorityDate | 1996-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.