http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0815859-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98cb1b197f761c87cd3caf32bc247e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34 |
| filingDate | 1997-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e7576c39050c5869764f01d8c5b4626 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15c5a98510be2a5b54f68d44eabaf028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0de59d9e092d48dbac7dd7bbc7f0457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3945ffab96e81ce854d9bc4f216587b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a29e3ac6e86f3b3fa120126301dd3bb7 |
| publicationDate | 1998-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0815859-A1 |
| titleOfInvention | Intimal thickening inhibitors |
| abstract | The present invention is directed to an intimalnhypertrophy inhibitor containing as the active ingredient annoxyindole derivative represented by the following formulan(I) or a salt thereof:n n(wherein R 1 represents a hydrogen atom; a phenyl group whichnmay be substituted by a lower alkyl group, a lower alkoxyngroup, a lower alkylaminoalkoxy group, a hydroxy group, annamino group, a lower alkylamino group, or a halogen atom; orna pyridyl group which may be substituted by a lower alkylngroup, a lower alkoxy group, a lower alkylaminoalkoxyngroup, a hydroxy group, an amino group, a lower alkylaminongroup, a halogen atom, a lower alkoxycarbonyl group, or ancarboxyl group; R 2 represents a phenyl group which may bensubstituted; or a pyridyl group which may be substituted byna lower alkyl group, a lower alkoxy group, a lowernalkylaminoalkoxy group, a hydroxy group, an amino group, anlower alkylamino group, a halogen atom, a lowernalkoxycarbonyl group, or a carboxyl group; R 3 represents anhydrogen atom; a lower alkyl, benzyl, or a benzenesulfonylngroup which may be substituted; or an acyl group; R 4 nrepresents a hydrogen atom; a lower alkoxy group, a halogennatom, an amino group, a lower alkylamino group, a carboxyl ngroup, a lower alkoxycarbonyl group; a phenylcarbomoyl groupnwhich may be substituted; or a trifluoromethyl group; Xnrepresents CH or N; n represents a number between 0 and 4ninclusive that indicates the number of substituents; and thenbroken/solid double line denotes a single bond or a doublenbond). The intimal hypertrophy inhibitor of the presentninvention exhibits excellent inhibitory action againstnintimal hypertrophy, and thus is useful as anpreventive/therapeutic/ameliorating agent for proliferativenvascular diseases such as restenosis after PTCA,narteriosclerosis, peripheral embolism, and angiitis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006105795-A1 |
| priorityDate | 1996-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 546.