| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
1996-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4534faca92f103d8f2eb19d278be7b5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86e3ead8f8f600fa90d17ada2470ef48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5fadb979bac3f29e8bfde995fee89f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f64bb206cbfe9cb2fdb013053d4147d |
| publicationDate |
1998-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0815197-A1 |
| titleOfInvention |
Long qt genes and method for diagnosing or preventing the occurrence of long qt syndrome |
| abstract |
The invention relates to the identification of the molecular basis of acquired long QT syndrome. More specifically, the invention has identified that HERG is associated with acquired long QT syndrome. HERG has been identified to encode the major subunit for the IKr channel. It has been found that increasing the extracellular levels of K<+> paradoxically increases the outward current of this channel. Increasing extracellular K<+> levels in patients, especially those being treated with antiarrhythmic medication or other medication which can cause cardiac arrhythmia or those with the hereditary form of long QT syndrome, decreases the likelihood of developing LQT and torsade de pointes. |
| priorityDate |
1995-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |