| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33c922e05f6133b7d72dbb849d77487d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-021 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 |
| filingDate |
1996-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90d919d36444d5d30afd5ad843902e33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15ae6c32b758521f48b17e7eb41c19b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82718bb4679c7574d9705e4c703a0cb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571066725b97b6adbf600e41c3b5d0fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc047f33f63c9b0bd323e175504774b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3934f13017e034135a2bcc4a5a3b50b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9481bca8667450b754be6c327c33e938
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd4f747ede3078be9c0c52da3f4a098
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6c6e3cdd6efcde814a2b46125cdb980 |
| publicationDate |
1997-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0812839-A1 |
| titleOfInvention |
Irreversible HIV protease inhibitors, compositions containing same and process for the preparation thereof |
| abstract |
The present invention relates to novel compounds of formula (I) which has inhibitory activities against human immunodeficiency virus ("HIV") protease, a process for the preparation thereof, and compositions for prevention or treatment of AIDS by HIV infection comprising the above compounds as active ingredients.n wherein:n R 1 is an aromatic group, a nitrogen-containing aromatic group, C 1-4 alkyl group optionally substituted with an aromatic group or a nitrogen-containing aromatic group, C 1-4 alkoxy group optionally substituted with an aromatic group or a nitrogen-containing aromatic group; R 2 is an amino acid residue or a C 1-8 alkyl group substituted with a C 1-4 alkylsulfonyl group; R 3 is a C 1-4 alkyl group optionally substituted with an aromatic group; R 4 is hydrogen or a C 1-2 alkyl group; R 5 is a C 1-10 alkyl group optionally substituted with an aromatic group; and n is 1 or 2. |
| priorityDate |
1994-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |