abstract |
An inflammatory cytokine production inhibitor containing a polyphenyl derivative represented by general formula (I) as the active ingredient, wherein R 1 and R 2 may be the same or different from each other and each represents hydrogen, C 1 -C 4 alkyl, C 2 -C 12 aliphatic acyl, C 7 -C 11 aromatic acyl or C 8 -C 12 arylaliphatic acyl; and n represents 0 to 2. The derivative has an excellent effect of inhibiting inflammatory cytokine production and an excellent effect of curing inflammatory intestinal diseases, such as ulcerous colitis and Crohn's disease, and Behcet's disease, so that it is useful as an inflammatory cytokine production inhibitor and a curative or preventive for inflammatory intestinal diseases and Behcet's disease. |