| abstract |
A compound represented by general formula (I), a medicinally acceptable salt or ester thereof, and an antineoplastic containing the same as the active ingredient, wherein Ar?1, Ar2, Ar3 and Ar4¿ represent each aryl or heteroaryl, A represents an optionally substituted hydrocarbon group; X and Y represent each oxygen, sulfur, carbonyl, -CHRa- (Ra being hydrogen or lower alkyl) or -NRb- (Rb being hydrogen or lower alkyl), or X and Y are combined together to represent vinylene or ethynylene; R?1, R2, R3, R8 and R9¿ represent each hydrogen, halogeno, hydroxy, lower alkyl or lower alkoxy; R?4 and R5¿ represent each hydrogen, halogeno, hydroxy, amino, nitro, cyano, carboxy, lower alkoxycarbonyl, carbamoyl, lower alkylcarbamoyl, lower alkyl, lower hydroxyalkyl, lower fluoroalkyl or lower alkoxy; R6 represents lower alkyl; and R7 represents hydrogen or lower alkyl; provided when one of X and Y represents oxygen, sulfur or -NRb-, the other of them represents carbonyl or -CHRa-. |