http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0804238-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a135a933620c99beab01d4ac785d25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d779448e816f508915ebf0e60c0ba809 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
filingDate | 1996-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b3226be0177d0040e5e2117338ba2c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48b6018ecedd1cf95034d50a0ea8bb3b |
publicationDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0804238-B1 |
titleOfInvention | Method to prevent transplant rejection |
abstract | A method for reducing the rejection of allografts comprising donor tissue containing antigen presenting cells (APC's), which method comprises: a) contacting the donor tissue with a photosensitizing agent to obtain a modified donor tissue; b) exposing the modified donor tissue to light having a wavelength absorbed by the photosensitizing agent for a time sufficient to deplete the APC's in the donor tissue; and c) transplanting the APC-depleted donor tissue into the tissue of a recipient. By subjecting donor tissue to photodynamic therapy, the mean survival time of grafts, particularly skin allografts, was significantly lengthened. The photosensitizer may also be part of a conjugate containing a target-specific moiety. |
priorityDate | 1995-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.