abstract |
Leukotriene B4 analogs of the formula I, <IMAGE> in which R <1>: the radical COOR <2> with R <2> in the meaning of a hydrogen atom or a (C1-C4) alkyl group or R <1> the rest CH2OH, B: an alkylene group with 1-3 C atoms in the chain, a residue <IMAGE> or a residue <IMAGE> with R <3> in the meaning of a hydrogen atom, a carboxy or methoxycarbonyl group, A: die Groups <IMAGE> -O-, <IMAGE> -NH-CO-, -CO-NH-, -OCH2-, -CH = CH-, -COCH2-, or -CHOH-CH2-, X: N or CH, D: the groups <IMAGE> and; <IMAGE>: mean a single or double bond, process for their preparation and their pharmaceutical use. |