| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15fd9c73822ad80e38eec3673024869a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 |
| filingDate |
1995-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5dd83093785f395029a0474bbf8e2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_578a3a04a652be5a2fbe7e8a95feaf57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14c79c3ae807d25c10249c91b45e224f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_248710f6ff15d4c0a9de8703a35835dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3096c849c94c831255800164ac464036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81724e590d9473a177e36ab68263f2bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c66942eef50555bedb38e7c4c8af41be |
| publicationDate |
1997-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0799240-A1 |
| titleOfInvention |
Heterocyclic keto arginine peptides as thrombin inhibitors |
| abstract |
This invention relates to new and useful inhibitors of the enzyme thrombin of the formula (I): AS - X, and more particularly compound (1) in the preparation, and pharmaceutical compositions. As well, this invention relates to the use of such compounds and compositions in vitro as anticoagulants and in vivo as agents for the treatment and prophylaxis of thrombotic disorders such as venous thrombosis, pulmonary embolism and arterial thrombosis resulting in acute ischemic events such as myocardial infarction or cerebral infarction. Moreover, these compounds and compositions have therapeutic utility for the prevention and treatment of coagulopathis associated with coronary bypass operations as well as restenotic events following transluminal angioplasty. |
| priorityDate |
1994-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |