| abstract |
The invention concerns novel 3-aryl-4-hydroxy- DELTA <3>-dihydrofuranone derivatives of formula (I), wherein: A and B together with the carbon atom to which they are bound form a five to seven member ring which is interrupted by at least one heteroatom and either unsubstituted or substituted; X represents alkyl, halogen or alkoxy; Y represents hydrogen, alkyl, halogen, alkoxy or halogenated alkyl; Z represents alkyl, halogen or alkoxy; n is 0, 1, 2 or 3; G represents hydrogen (a) or one of the groups (b), (c), (d), (e), (f) or (g) shown; E represents a metal ion equivalent or an ammonium ion; L represents oxygen or sulphur; and R<1>, R<2>, R<3>, R<4>, R<5>, R<6> and R<7> have the meanings indicated in the description. The invention also concerns methods of producing the said compounds and the use of the said compounds as anti-parasitic agents, as well as intermediate products of formula (II) in which R<8> represents alkyl. |