abstract |
The invention relates to a compound of the formulan wherein R is hydroxy and R 1 is H 2 or CH 2 , or R is hydrogen or fluoro and R 1 is CH 2 . n Compounds of formula I are useful as agents for the treatment of hyperproliferative skin diseases, such as psoriasis, neoplastic diseases, such as leukemia, and sebaceous gland diseases, such as acne and sebhorreic dermatitis. |