http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0792159-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58833d6c0dc5cfab5bbd7e8354619752 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate | 1995-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92dbb2ddc49c83a1d7aee95919a4fc15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_314dbfb6d261579a0a9914bcaad6a987 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25359f0512de31423010ec9c18ad68af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d4dbcaf73a01d9580baae3f0a61436d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf9a664ec609581970349b22d7620f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be0696093bd7a9dceda58ebb4efe962e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72bd550cfa342bb1eff037d771a2662a |
| publicationDate | 1997-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0792159-A1 |
| titleOfInvention | Human calcium sensor protein, fragments thereof and dna encoding same |
| abstract | The present invention relates to the isolation of a cDNA clone encoding the calcium sensor in human placenta and subsequent Northern blots confirming the mRNA expression also in human parathyroid and kidney tubule cells. Close sequence similarity is demonstrated with the rat Heymann nephritis antigen, a glycoprotein of the kidney tubule brush border with calcium binding ability. Immunohistochemistry substantiates a tissue distribution of the calcium sensor protein similar to that previously described for the Heymann antigen. It is proposed that the identified calcium sensor protein constitutes a universal sensor for recognition of variation in extracellular calcium, and that it plays a key role for calcium regulation via different organ systems. The calcium sensor protein belongs to the LDL-superfamily of glycoproteins, claimed to function primarily as protein receptors, but with functionally important calcium binding capacity. |
| priorityDate | 1994-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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