abstract |
Substituted thiophenylalkenylcarboxylic acid guanidides of the formula I are described wherein R (1) to R (5) have the meanings given in the claims, are outstandingly effective antiarrhythmic drugs with a cardioprotective component and are outstandingly suitable for the prevention of infarction and treatment of the infarct, as well as for the treatment of angina pectoris, while also preventing the pathophysiological processes in the development Inhibit or greatly reduce ischemically induced damage, especially when triggering ischemically induced cardiac arrhythmias. |