Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_269dc5c69a5c945148f54aefcb35dc20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 |
filingDate |
1995-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d32f028fb7a574c2e452f02b65af389a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b902ca4820c5cd25376cc5e93e2f91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11af8cb33bdc3b3e2394ee3cc8abc793 |
publicationDate |
2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0789777-B1 |
titleOfInvention |
Polysaccharides having a high iduronic acid content |
abstract |
PCT No. PCT/EP95/04241 Sec. 371 Date Apr. 12, 1996 Sec. 102(e) Date Apr. 12, 1996 PCT Filed Oct. 30, 1995 PCT Pub. No. WO96/14425 PCT Pub. Date May 17, 1995Process for the preparation of polysaccharides having a high iduronic acid content comprising: a) N-deacetylation of the polysaccharide K5 from E. coli or of the heparan sulfate or O-desulfation of heparin or heparan sulfate; b) N-sulfation of the product obtained from the stage a); c) epimerization in presence of the C5 epimerase enzyme; d) sulfation of at least some free hydroxy groups, wherein the stage c) is carried out in a reaction medium constituted by a classical buffer solution formed by HEPES, potassium chloride, EDTA and TRITON X-100 to which a suitable additive is added. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139876-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9068957-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7575886-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7947507-B2 |
priorityDate |
1994-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |