| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18773e0994d80743ef5939ace79050bb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-128
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0442
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-29 |
| filingDate |
1995-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11ccf66e1a1fa2c2ba4b26278369eb7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aceb24561717abc45e128108c777e501 |
| publicationDate |
1997-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0788376-A2 |
| titleOfInvention |
Calixarene conjugates useful as mri and ct diagnostic imaging agents |
| abstract |
Calixarene conjugates useful for imaging, particularly magnetic resonance imaging (MRI) and computed tomography (CT) are described. Said calixarene conjugates comprise (i) a calixarene backbone, and (ii) at least one imaging moiety linked thereto, and may be of formula (II) wherein at least one of the R?1 and R4¿ substituents comprises an imaging moiety, the remaining R?1 and R4¿ substituents are spectator groups, J is an ortho-linker, and n is an integer from 4 to 8. Imaging moieties useful for CT imaging include those comprising two or more iodine atoms. Imaging moieties useful for MRI include (i) organic moieties comprising four or more fluorine atoms; (ii) nitroxyl spin labeled moieties; and (iii) metal chelate moieties. |
| priorityDate |
1994-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |