http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0778823-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-24 |
| filingDate | 1995-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4b9e39163c20b8da7f3d626fa90780b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dd5e6dd3dc74d99626a5d41769621da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82731f59265ae3c40d5d1a7b5d924220 |
| publicationDate | 1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0778823-A1 |
| titleOfInvention | Process for reducing amino acids and derivatives thereof |
| abstract | PCT No. PCT/EP95/03281 Sec. 371 Date Mar. 3, 1997 Sec. 102(e) Date Mar. 3, 1997 PCT Filed Aug. 17, 1996 PCT Pub. No. WO96/07634 PCT Pub. Date Mar. 14, 1996A process is disclosed for reducing amino acids and derivatives thereof Compounds of formula (I), in which n=0 or 1 and R1, R2, R3, R4, R5 and R6 have the meanings given in the description, are reduced to the corresponding amino alcohols of formula (II): the formula (I) compounds are converted in a first step, in at least one alcohol and with the addition of acid and heat to an ester, this process producing a reaction mixture containing the ester; the ester is converted in a second reaction step with alkali or alkaline earth borohydride to compounds of formula II. By specifying that the second step be carried out without isolating the ester from the reaction mixture and by using alkali or alkaline earth borohydrides which are not activated, the invention facilitates the production from amino acids and their derivatives of the correponding alcohols in a simple "single vessel" process, with high yields and in such a way as to preserve a given centre of chirality. Applications: synthesis components, preparation of optically active compounds splitting of racemic compounds. <IMAGE> (I) <IMAGE> (II) |
| priorityDate | 1994-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.