http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0778282-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 |
filingDate | 1996-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e360f58e669d67426b4cb781575649e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68adb848902a954f3c4a9a72c8d2bedc |
publicationDate | 1997-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0778282-A1 |
titleOfInvention | Process for producing etoposide |
abstract | A protected 4'-demethyl-4-epipodophyllotoxin is reacted with a protected glucose derivative in a non-halogen type organic solvent in a 0.1 to 7-fold-part by volume based on 1 part by weight of the protected 4'demethyl-4-epipodophyllotoxin to give an etoposide derivative of formula (3) which is protected at its functional groups:n wherein each of R 1 and R 2 each is a protective group for hydroxy, if necessary, followed by removal of these protective groups. By use of the non-halogen type organic solvent in lieu of any harmful halogen type solvent, formation of undesirable by-products can be minimized so that the etoposides can be obtained in a high yield and high purity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6384201-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0240489-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6894075-B2 |
priorityDate | 1995-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 191.