http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0777650-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 |
| filingDate | 1995-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_123b8ffcaf5460cda2002f105db51a95 |
| publicationDate | 1997-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0777650-A1 |
| titleOfInvention | Biphenylamide derivatives as 5ht 1d? antagonists |
| abstract | PCT No. PCT/EP95/03226 Sec. 371 Date Feb. 21, 1997 Sec. 102(e) Date Feb. 21, 1997 PCT Filed Aug. 14, 1995 PCT Pub. No. WO96/06079 PCT Pub. Date Feb. 29, 1996Compounds of formula (I) or a salt thereof:yl, C3-6cycloalkyl, COC1-6alkyl, C1-6alkoxy, hydroxy, hydroxyC1-6alkyl, hydroxyC1-6alkoxy, C1-6alkoxyC1-6alkoxy, acyl, nitro, trifluoromethyl, cyano, CHO, SR9, SOR9, SO2R9, SO2NR10R11, CO2R10, NR10SO2R11, CONR10R11, CO2NR10R11, CONR10(CH2)pCO2R11, (CH2)pNR10R11, (CH2)pCONR10R11, (CH2)pNR10COR11, (CH2)pCO2C1-6alkyl, CO2(CH2)pOR10, CONHNR10R11, NR10R11, NR10CO2R11, NR10CONR10R11, CR10=NOR11, CNR10=NOR11, where R10 and R11 are independently hydrogen or C1-6alkyl and p is 1 to 4; R2 and R3 are independently hydrogen, halogen, C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkenyl, C1-6alkoxy, acyl, aryl, acyloxy, hydroxy, nitro, trifluoromethyl, cyano, hydroxyC1-6alkyl, C1-6alkylOC1-6alkyl, CO2R10, CONR10R11, NR10R11 where R10 and R11 are independently hydrogen or C1-6alkyl; R4 and R5 are independently hydrogen or C1-6alkyl; R6 is hydrogen, halogen, hydroxy, C1-6alkyl or C1-6alkoxy; R7 and R8 are independently hydrogen, C1-6alkyl, aralkyl, or together with the nitrogen atom to which they are attached form an optionally substituted 5-7-membered heterocyclic ring containing one or two heteroatoms selected from oxygen, nitrogen or sulphur; A is oxygen, S(O)q where q is 0, 1 or 2, CR4=CR5 or CR4R5 where R4 and R5 are independently hydrogen or C1-6alkyl, or A is NR12 where R12 is hydrogen or C1-6alkyl; B is (CR13R14)q where q is 2, 3 or 4 and R13 and R14 are independently hydrogen or C1-6alkyl or B is (CR13R14)r-D where r is 0, 1, 2 or 3 and D is oxygen, sulphur or CR13=CR14; m is 1 to 4; and n is 1 or 2, exhibit 5HT1D antagonist activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020183011-A1 |
| priorityDate | 1994-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 148.