abstract |
The invention relates to peptides of the antigen Sm-D, consisting of 35 to 45 amino acids, which form a conformation epitope and can bind autoantibodies, such as occur in systemic lupus erythematosus (SLE). The peptide composed of 37 amino acids with the structure VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR or its mutants and variants is particularly preferred. |