http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0775152-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6420d04b0d68f339771080e32bd0fbc9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 |
filingDate | 1995-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cd3b5a23c9660bd91774537be5bc719 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_068c6903605a868a8001ece29e4d4311 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c90087f40cc255664097f05eb7f85f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d84c802a741d46fda12547ac7e5ca8 |
publicationDate | 1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0775152-A1 |
titleOfInvention | Synthesis of 4-alkoxy-n-acetylneuraminic acid |
abstract | This invention relates to an improved process for the synthesis of 4-alkoxy-N-acetylneuraminic acids. According to the process of the invention, N-acetylneuraminic acid is first alkylated at C-1 and C-2 and then the vicinal hydroxyl groups at C-8 and C-9 are protected through the formation of a ketal. The resulting protected alkyl ester alkyl ketoside is then alkylated at the C-4 position whereby the hydrogen of the C-4 hydroxyl group is replaced with an alkyl group to form an alkoxy group. Deprotection is accomplished through the removal of the ketal group at C-8 and C-9 and removal of the alkyl groups at C-1 and C-2, thereby producing the 4-alkoxy-N-acetylneuraminic acid. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10342812-B2 |
priorityDate | 1994-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 391.