http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0774966-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-80 |
| filingDate | 1995-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1a9ca2f1361f05a4ccddbd4c6b02617 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc7bdfcd709c42422cb6b88b05849d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d21329ff0d03e7f705912a334336643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5df281d89fd3653b77c632bd4ef35fa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e8bec2c4481064cb1d64d6f4c4abb96 |
| publicationDate | 1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0774966-A1 |
| titleOfInvention | Benzofuran compounds, compositions, and methods |
| abstract | The present invention provides novel, reduced benzothiophenes of formula IwhereinR is -H, -OH, -O(C1-C4 alkyl), -O-CO-(C1-C6 alkyl), -O-CO-Ar in which Ar is optionally substituted phenyl, or -O-SO2-(C4-C6 alkyl);R<1 >is -H, -OH, -O(C1-C4 alkyl), -O-CO-(C1-C6 alkyl), -O-CO-Ar in which Ar is optionally substituted phenyl, -O-SO2-(C4-C6 alkyl) chloro or bromo;n is 2 or 3; andR<2 >and R<3 >each are independently C1-C4 alkyl, or combine to form 1-piperidinyl, 1-pyrrolidino, methyl-1-pyrrolidino, dimethyl-1-pyrrolidino, 4-morpholino or 1-hexamethyleneimino; or a pharmaceutically acceptable salt thereof. Further provided are methods for alleviating the symptoms of post-menopausal syndrome, and inhibiting endometriosis, uterine fibrosis, and aortal smooth muscle cell proliferation. Also provided are pharmaceutical formulations with formula I compounds, optionally including estrogen or progestin, and intermediate compounds. |
| priorityDate | 1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 561.