abstract |
The present invention relates to compounds represesnted by formula (I):n wherein Z represents Gly or Cys; X represents an α-amino acid residue; Y represents a natural calcitonin moiety, a partial natural calcitonin peptide moiety, or a natural calcitonin-like peptide moiety; m represents an integer of 5-8, α-amino acid residues represented by X being the same or different; and n represents an integer of 0-3; provided that when m is 5, the sequence of 4 C-terminal residues of -(X) m - is different from the sequence of the third to sixth amino acids of natural calcitonin, nand pharmaceutically acceptable salts thereof. |