Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebb6a553affdc364c91cffe3baf12564 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 |
filingDate |
1995-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25d7d7f849fcb9a49d98a78db2f0d5c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ac5414785e5db896dbfb95b484940cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a7c2fda7cfd0c607685b8cb6bc89594 |
publicationDate |
1997-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0766662-A1 |
titleOfInvention |
Asymmetric synthesis of (r)- and (s)-arylethanolamines from iminoketones |
abstract |
A method for the enantioselective reduction of an α-iminoketone to an α-aminoalcohol is disclosed. The method utilizes a borane reducing agent as the reducing agent and a chiral 1,3,2-oxazaborole as the catalyst. The method is applied to the synthesis of R-albuterol from methyl 5-acetylsalicylate in high yield and high optical purity. |
priorityDate |
1994-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |