| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9fbfeba067df93dd1d2b4417267540f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072 |
| filingDate |
1995-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad099c28df2a8013afa63716b835cdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a23d9a7874c67f70be787c49f625e3e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e94775de2159e41efebbe97974e465e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd0478bab281f61404fd3ce17f2ba29 |
| publicationDate |
1997-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0765338-A1 |
| titleOfInvention |
Arginine mimic derivatives as enzyme inhibitors |
| abstract |
The present invention provides peptide aldehydes having an azetidinyl, prolyl or pipecolyl group as part of the peptide backbone and an arginine mimic group such as an amidinopiperidine or amidinophenyl tail. These compounds are potent and specific inhibitors of thrombin. Their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis are also described. |
| priorityDate |
1994-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |