http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0759425-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-822 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-821 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-56 |
| filingDate | 1996-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0574b95fad84f31ca63201b057703938 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03a35a926ab1cc31272d039cfd6517bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b871548a5a2f2c0a91eab8e68de3f0f8 |
| publicationDate | 1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0759425-A3 |
| titleOfInvention | Process for the preparation of optically active 1-aryl-alkylamines |
| abstract | a) 2-Aryl-propensäuren der Formeln nmit Wasserstoff in Gegenwart eines chiralen Komplexes aus einem Übergangsmetallsalznund einem chiralen Bisphosphin, sowie in Gegenwart einesnVerdünnungsmittels und gegebenenfalls in Gegenwart eines tertiären Aminsnumsetzt, b) die dabei entstehenden optisch aktiven 2-Aryl-propansäuren der Formel n nzunächst mit Thionylchlorid, gegebenenfalls in Gegenwart eines Verdünnungsmittels, und dann mit Ammoniak,ngegebenenfalls in Gegenwart eines Verdünnungsmittels und gegebenenfalls in Gegenwart eines Katalysators,numsetzt und c) die dabei erhaltenen optisch aktiven 2-Aryl-propansäureamide der Formeln nmit Natriumhypochlorit oder Natriumhpobromit in Gegenwart von Wasser umsetzt. According to a new process, optically active 1-aryl-alkylamines of the formula can be used in which R 1 and Ar have the meanings given in the description, manufacture by a) 2-aryl-propenoic acids of the formula with hydrogen in the presence of a chiral complex of a transition metal salt and a chiral bisphosphine, as well as in the presence of a diluent and optionally in the presence of a tertiary amine, b) the resulting optically active 2-aryl-propanoic acids of the formula first with thionyl chloride, optionally in the presence of a diluent, and then with ammonia, optionally in the presence of a diluent and optionally in the presence of a catalyst, and c) the optically active 2-aryl-propanoic acid amides of the formula obtained in this way reacted with sodium hypochlorite or sodium hypobromite in the presence of water. |
| priorityDate | 1995-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.