http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0754762-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 1995-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e5b692c86c278ea4048b10966beceb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f16570e45dc63011c3cb02c61646250 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc2379f3cd2fcf7121d683e9b2ce6797 |
| publicationDate | 1997-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0754762-A1 |
| titleOfInvention | Oligonucleotide for use in checking presence or absence of mutation in human-derived cytochrome p45oiic18 gene |
| abstract | An oligonucleotide which can hybridize with a human-derived cytochrome P450IIC18 gene, one of the enzymes participating in the metabolic decomposition of medicines, has a GC content of 40-70 %, and comprises 8 to 500 nucleotide units. The use of the oligonucleotide in the recognition or amplification of a DNA having the base sequence of this gene enables the presence or absence of mutation to be readily diagnosed and analyzed before the administration of a medicine. Thus it becomes possible to determine a safe dose of a medicine which has been difficult to use because of the occurrence of individual difference in drug-metabolizing function and to use also a medicine which takes an active form by the action of this enzyme according to individuals. |
| priorityDate | 1994-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.