http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0753076-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1072 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate | 1995-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fcf55ce1162608964426affed7a073d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef1221a7cebd245aeb9998ee4509cc1d |
| publicationDate | 1997-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0753076-A1 |
| titleOfInvention | Methods of identifying inducible inhibitors of transformation progression |
| abstract | This invention provides a method of identifying a progression suppressor gene which comprises: a) introducing DNA containing a progression gene into a population of transformed cells; b) treating the introduced transformed cells from step (a) so as to induce the expression of at least one progression suppressor gene and cause a subpopulation of the cells to revert to a characteristic phenotype; c) selecting cells which express the progression suppressor gene and exhibit the characteristic phenotype; d) isolating mRNA from the cells from step (c); e) comparing the mRNA so obtained with mRNA obtained from the uninduced transformed cells as to identify mRNA expressed only by the cells from step (c); and f) isolating the gene encoding such mRNA so as to thereby identify the progression suppressor gene. |
| priorityDate | 1994-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 373.