Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70571 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
1995-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_462f545191775d93a525761a53a9fd2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18894d909bab0a2bca94d9fb7b18bf47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d6a1309065c286d7fc0c2fdbd30a04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b74f11fb17beb893fd79018de1174898 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c075594789f73c69f39b2114355039 |
publicationDate |
1997-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0753064-A1 |
titleOfInvention |
Method for the permanent expression of glutamate receptors |
abstract |
The invention concerns a method for the preparation of eucaryotic cell lines for the permanently ectopic expression of glutamate receptors, the cell lines being prepared by the transformation of cells containing nucleic acids coding for glutamate receptors. The method is characterized in that, during the establishment of the cell lines, at least one of the following conditions is satisfied for the culture: a) the transformed cells are cultured in a culture medium containing a glutamate precursor; b) the transformed cells are cultured in the presence of a glutamate-receptor antagonist; c) the transformed cells are cultured in a first phase under conditions in which glutamate-receptor expression is repressed and in a second phase under conditions in which the repression is discontinued. The invention also concerns the cell lines thus obtained and their use. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6649746-B1 |
priorityDate |
1994-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |