http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0747344-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5976ba69a401cf70e6f8d1978e47a82 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 |
filingDate | 1996-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1998-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7d4d23ea126a67364a88717e422e6f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e838e5333eab20860d8c6b32ccdcb1d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdb4b4e906c217983621fe292e0f7ca2 |
publicationDate | 1998-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0747344-B1 |
titleOfInvention | Process for the purification and crystallisation of iopamidol |
abstract | The present invention describes a process for the purification and crystallisation of lopamidol, wherein 1-propanol, or 2-propanol, is added to an aqueous solution of lopamidol followed, if necessary, by azeotropic distillation to reduce the quantity of water in relation to the quantity of propanol, and thereby ensure an high yield. The aqueous solution can be prepared either by the dissolution of crude lopamidol in water or directly from the reaction in which the lopamidol is formed. The present invention presents advantages for the routine production of lopamidol since the crystallisation is straighfforward to perform, can be easily controlled and is reproducible at an industrial scale. |
priorityDate | 1995-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.