abstract |
A method of modulating NF-kB transcription factor comprising administering to a human in need thereof an effective amount of a compound having the formulan n wherein R 1 and R 3 are independently hydrogen, -CH 3 ,n wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof. |