| abstract |
An imidazoline derivative or possible tautomer thereof, represented by the formula (1), wherein n represents one of integers "1" through "4", and R 1 and R 2 represent hydrogen atom, lower alkyl, aryl, aralkyl group, or R 1 and R 2 cooperate to represent alkylene, alkylidene or arylalkylidene group, while R 3 represents a nitrogen-containing aromatic ring that may be substituted by lower alkyl, alkoxy or alkanoyl group, or a substituted phenyl group represented by the formula (2), wherein R 4 and R 5 represent hydrogen atom, lower alkyl group that may be substituted by halogen atom or hydroxyl group, cycloalkylalkyl group, lower alkenyl group, lower alkanoyl group that may be substituted by halogen atom, lower alkoxyalkyl or alkoxycarbonyl group, arylcarbonyl, arylalkyl or arylalkoxycarbonyl group, lower alkylaminocarbonyl or alkylsulfonyl group or arylsulfonyl group, or R 4 and R 5 cooperate with an adjacent nitrogen atom to constitute a cyclic structure, while R 6 represents hydrogen atom, hydroxyl group, halogen atom, lower alkyl or alkoxy group or nitro group. |