| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efaece3f57d915a44fb0784b21caeab8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate |
1995-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ae90d60f5eb7e03a022bb3c28dd1acb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03dbc0d0dcea72d6a9fe402b91bb1963 |
| publicationDate |
1996-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0732921-A1 |
| titleOfInvention |
C-glycoside analogues of n-(4-hydroxyphenyl)retinamide-o-glucuronide |
| abstract |
The present invention provides breast cancer chemopreventive arylamide analogues of retinoic acid, more particularly C-glycoside analogues of N-(4-hydroxyphenyl)retinamide-O-glucuronide and N-glycoside analogue of retinoyl β-glucuronide that resist both β-glucuronidase mediated enzymatic hydrolysis as well as acid catalyzed hydrolysis. Specifically, the drugs include 4-(retinamido)phenyl-C-glucuronide; 4-(retinamido)phenyl-C-glucoside; 4-(retinamido)benzyl-C-xyloside; 4-(retinamido)benzyl-C-glucoside; 4-(retinamido)benzyl-C-glucuronide; 4-(retinamido)phenyl-C-xyloside, 1-(B-D-glucopyranosyl)retinamide and 1-(D-glucopyranosyluronosyl)retinamide. The invention also relates to a method for making such drugs. |
| priorityDate |
1994-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |