| abstract |
Disclosed is a 2-oxoindoline derivative represented by the formula (I):n (wherein Ring A represents a substituted or unsubstituted benzene ring, R 1 represents H, a cycloalkyl group, an aryl group, a nitrogen-containing heterocyclic group, an oxygen-containing heterocyclic group, a sulfur-containing heterocyclic group, a heterocyclic group containing N and O, a heterocyclic group containing N and S, a lower alkoxy group, a carboxyl group, cyano group, a lower alkylthio group, a lower alkylsulfinyl group, a lower alkylsulfonyl group, an oxiranyl group or a 2-(lower alkylthio)-1-hydroxyethyl group, R 2 represents an aryl group, a group represented by the formula:n a substituted or unsubstituted nitrogen-containing heteromonocyclic group, a substituted or unsubstituted nitrogen-containing heterobicyclic group, a group represented by the formula:n (wherein n represents 1 or 2.), nan oxygen-containing heterocyclic group, a sulfur-containing heterocyclic group, a heterocyclic group containing N and O or a heterocyclic group containing N and S, R 3 represents a substituted or unsubstituted lower alkyl group, Q represents a single bonding arm or a lower alkylene group, Y represents a single bonding arm, a lower alkylene group or a lower alkenylene group.), nand a pharmaceutically acceptable salt thereof. |