| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82980f9308582ae872148dad95e35c44 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2013-00472
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2013-00221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-434
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-418 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F13-0203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00 |
| filingDate |
1994-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f82e0179c6b50ffe0c2709b8c4184f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e778861e0e664767f82a12673a7f3f90 |
| publicationDate |
2004-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0726749-B1 |
| titleOfInvention |
Hemostatic patch |
| abstract |
A fibrogen-free substrate having as a hemostatic agent on a surface thereof a mixture of a clot-promoting amount of thrombin and an amount of epsilon aminocaproic acid (EACA) effective to accelerate the rate of blood clotting induced by the thrombin is useful as a hemostatic patch which is safe, inexpensive and which rapidly controls bleeding from a wound. A patch which rapidly stanches the flow of blood from a lesion on a parenchymal organ by pressing it against the surface of the organ for 3-5 minutes, is produced by applying thrombin, EACA and CaCl2 to a rigid sheet of biodegradable foam, such as an absorbable gelatin sponge, and compressing the dry sheet to produce a flexible sheet which conforms to the contour of the organ without the necessity of pre-moistening. The problem associated with thrombin-fibrinogen glues of adhesion of the wounded surface of the organ to adjacent tissue is avoided by applying the hemostatic agent to only the wound-contacting face of the sheet. |
| priorityDate |
1993-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |