http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0725795-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 |
filingDate | 1995-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e96a1a0656fd4ba6a922f32729c868 |
publicationDate | 1996-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0725795-A1 |
titleOfInvention | Single-chain forms of the glycoprotein hormone quartet |
abstract | Single-chain forms of the glycoprotein hormone quartet, at least some members of which are found in most vertebrates, are disclosed. In one embodiment of these single-chain forms, the alpha and beta subunits of the wild-type heterodimers or their variants are covalently linked, optionally through a linker moiety. A drug may further be included within the linker moiety to be targeted to receptors for these hormones. Some of the single-chain forms are agonists and others antagonists of the glycoprotein hormone activity. Another embodiment of the single-chain compounds of the invention comprises two beta subunits of the glycoprotein hormones, which beta subunits are the same or different. These "two- beta " forms are antagonists of glycoprotein hormone activity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014159813-A1 |
priorityDate | 1994-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.