abstract |
PCT No. PCT/EP94/02687 Sec. 371 Date Apr. 4, 1996 Sec. 102(e) Date Apr. 4, 1996 PCT Filed Aug. 11, 1994 PCT Pub. No. WO95/06723 PCT Pub. Date Mar. 9, 1995A method of marking a eukaryotic (mammalian) cell by expressing in this cell a nucleic acid, said nucleic acid encoding a cell surface receptor, and by subsequently presenting said receptor at the cell surface, characterized by using a nucleic acid in which the region encoding the intracellular domain of the receptor has been completely or party deleted or modified in such a way that the receptor presented at the surface cannot, after binding to its binding partner, effect any signal transduction, is effective and usable in gene therapy. |