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filingDate 1995-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f82cf640fc8a22bb26c022c0603bbc90
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publicationDate 2002-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0721785-B1
titleOfInvention Debittered ranitidine preparation
abstract Ranitidine (i.e. N-(2(((-5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-meth yl-2-nitro-1,1-ethenediamine) prepn. comprises a salt of ranitidine with a polycarboxylic acid. The ranitidine prepn. is pref. in an aq. soln. The prepn. contains an equiv. amt. of polycarboxylic acid carboxylate gps./mol. ranitidine. The polycarboxylic acid has a mol. wt. of ≥ 1000 Dalton, pref. a carboxyl equiv. wt. of 72-800 Dalton, and is esp. an alkali-soluble acrylic acid and/or methacrylic acid polymerisate or copolymerisate. The polymerisate or copolymerisate comprises 10-100 wt.% acrylic acid and/or methacrylic acid units and 90- wt.% lower alkyl acrylate and/or lower alkyl methacrylate units.
priorityDate 1994-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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