Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c7d1e0bf0efe57c98ba543afd5bf966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_884170daee0baff8400371fa096c4d27 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-31 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 |
filingDate |
1995-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_020ab1894d54765b5445d10c35a32a66 |
publicationDate |
1996-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0721013-A1 |
titleOfInvention |
New staphylokinase derivatives |
abstract |
The invention relates to staphylokinase derivatives showing a reduced immunogenicity as compared to wild-type staphylokinase. To achieve this the invention provides staphylokinase derivatives having essentially the amino acid sequence of wild-type staphylokinase but wherein at least one immunodominant epitope is eliminated without destroying the biological activity of the derivatives. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2339430-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9852976-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1724282-A3 |
priorityDate |
1995-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |