| abstract |
Process for the preparation of E-oxime ethers of phenylglyoxylic acid esters of the general formula I n<IMAGE>n in which the variables have the following meanings: n n the substituents X and Y are selected from a group comprising halogen, C1-C4-alkyl, C1-C4-alkoxy or trifluoromethyl; n m is an integer from 0 to 4; n n is an integer from 0 to 3,n and in which n n a) a phenol of the general formula II n<IMAGE>n is converted into the phenolate, n b) the latter is mixed with a lactone of the general formula III n<IMAGE>n n c) the molten mixture is reacted, and n d) the resulting 2-phenoxymethylbenzoic acid of the general formula IV n<IMAGE>n is converted, via the acid chloride, into the benzoyl cyanide and this is converted into the corresponding alpha-keto acid, which is converted into the compound I. n n Alternatively, the compound IV can be converted, via the ester, into the beta-keto sulphoxide, which is reacted to give the beta-keto ester, which is subsequently converted into the compound I. |