http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0710234-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-38 |
| filingDate | 1994-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5a87cbf230c510477fd7b0efddd3f6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78458648e3a41905338d68d3f5eaeb07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bed8894a724634c2f8e86163dcd22a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_096b6c5c23787e59e86eb9a8efbfb75c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a9fbf71f01344fbbc2e28b0195df418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f588fa4d431ada4abd158f7fa3f1eaae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f23ca60cc616e98e9db38437573628fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0896321fde5f32af4637de256ef7135e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_204b6fc970c1082c1baeee3f53fe6e3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_128ee0c007279f6eb2c8612b222b64ce |
| publicationDate | 1996-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0710234-A1 |
| titleOfInvention | Isoflavone derivatives |
| abstract | The present invention relates to isoflavone, isoflavan-4-one and isoflavane derivatives of general formula (I), their salts, pharmaceutical compositions containing the compounds of general formula (I), and to a process for preparing the same. In general formula (I), if n is 0, R?5 and R6¿ together stand for an oxo group and the dotted line means a double bond, R1 represents C¿1-18?alkyl substituted by alkylcarbonyl, carboxy, sulfonic acid, hydroxy, phenoxy, piperidino, morpholino or piridino or by a (C1-4alkyl)2N-(CH2)mCO(CH2)p- or by (C1-4alkyl)2N-(CH2)mOCO(CH2)p- group; or stands for C3-6cycloalkyl or cycloalkenyl; or if n is 1, R?5 and R6¿ together stand for an oxo group and the dotted line means a double bond, R1 represents C¿1-18?alkyl optionally substituted by alkyl-carbonyl, alkoxycarbonyl, carboxy, sulfonic acid, hydroxy, phenoxy, piperidino, morpholino or piridino or by a (C1-4alkyl)2N-(CH2)mCO(CH2)p- group; or stands for C3-6-cycloalkyl or cycloalkenyl or C2-6alkenyl; or if n is 0 or 1, R?5 and R6¿ together stand for an oxo group or stand separately for hydrogen and the dotted line does not mean a chemical bond, R1 represents C¿1-18?alkyl optionally substituted by alkyl-carbonyl, alkoxycarbonyl, carboxy, sulfonic acid, hydroxy, alkoxy, phenyl optionally substituted by a halo atom, phenoxy, piperidino, morpholino or piridino or by a (C1-4alkyl)2N-(CH2)mCO(CH2)p- group; or stands for C3-6-cycloalkyl or C2-6alkenyl; or R stands for C1-8alkyl, halogen, C1-4alkoxymethyl, C2-5-acyloxymethyl, or hydroxymethyl; R?4¿ stands for hydrogen or C¿1-4?alkyl; R?2 and R3¿ stand for hydrogen or C¿1-6?alkoxy; R?5 and R6¿ together stand for an oxo group or separately stand for hydrogen; the dotted line means a double bond being optionally present; n is 0 or 1; m is an integer from 1 to 4; and p is an integer from 1 to 4. The compounds of general formula (I) can be used for the prevention and treatment of osteoporosis. They are prepared by methods well known in the organic chemistry. |
| priorityDate | 1993-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 494.