| abstract |
A process for the preparation of multinuclear aromatic compounds by cross-coupling of terminal alkynes with aromatic halogen compounds or - perfluoroalkyl sulfonates with palladium catalysis in the presence of at least one water-soluble complex ligand, characterized in that the reaction medium forms an aqueous and an organic phase and the palladium in the form of an organic phase soluble palladium compound or in solid form as palladium metal, in particular applied to a support.n n n The reaction according to the invention proceeds chemoselectively, so that even electrophilic groups, such as esters or nitriles, do not impair the course of the reaction.n n n The process according to the invention makes it possible to produce organic compounds economically in very good yields and at the same time very high purity, in particular without contamination by the complex ligands. |