http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0703791-A4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_889600ff9c2ccc2a98b5f7dbb0bd5f6f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
filingDate | 1993-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_757cf4f6160160563573d22d60b5a481 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4addcf058d53000d3af1187a94ec1010 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09379b946a96ba1ffd7d5fdd2e6fe19f |
publicationDate | 1996-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0703791-A4 |
titleOfInvention | IODATED NEURO PROBE TO DETECT MONOAMINE RECOVERY LOCATIONS |
abstract | An iodinated neuroprobe is provided for mapping monoamine reuptake sites. The iodinated neuroprobe is of the formula: <IMAGE> wherein R=a CnH2n+1 group where n=0-6, an alkenyl group, a monofluoroalkyl group including nF where n=18 or 19, or a mCnH2n+1 group where n=1-6 and where m=11 or 14 for at least one mC; R'=a CnH2n+1 group where n=0-6, a p-iodophenylmethyl group, a p-iodophenylethyl group, a phenylmethyl group, or a phenylethyl group; X=an isotope of F, an isotope of Cl, an isotope of Br, an isotope of I, CH3, or Sn(R''1R''2R''3); R''1=a CnH2n+1 group where n=1-6, or an aryl group; R''2=a CnH2n+1 group where n=1-6, or an aryl group; R''3=a CnH2n+1 group where n=1-6, or an aryl group; and Y=H only if X is an isotope of I, or R' is a p-iodophenylmethyl group, or R' is a p-iodophenylethyl group, else Y=an isotope of I. Related analogs are also provided. Additionally, a precursor of a radiolabled neuroprobe and a kit for preparing the iodinated neuroprobe are provided. |
priorityDate | 1992-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.