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filingDate 1995-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b4f0eef3a415cc7dbf6ba0613ff29de
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publicationDate 1997-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0696576-A3
titleOfInvention Process for the preparation of 2-amino-2-arylethanols and new intermediates
abstract Prodn. of 2-amino-2-arylethanols of formula Ar-CH(NH2)-CH2OH (I) comprises catalytically hydrogenating a 2-hydroxy-1-aryl-ethanone oxime of formula Ar-C(=NOH)-CH2OH (II) using a Raney nickel or cobalt catalyst in a diluent and in the presence of a base. Ar = aryl or heteroaryl opt. mono- to penta-substd. by halo, alkyl or alkoxy (opt. substd. by halo), or opt. substd. cycloalkyloxy or phenyl.
priorityDate 1994-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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