Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-095 |
filingDate |
1994-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c0300489c03b7828ed84004d363f71b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_551773fe8a035d3bad7dbc1c91268261 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2860fcb88633c9922ed8bdc7c9dd36fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27ba2036f8ad24567d75545d92e92739 |
publicationDate |
1996-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0694066-A1 |
titleOfInvention |
Model for gonococcal infection |
abstract |
An animal having a disseminated infection with an organism requiring human factor C1q binding for pathogenicity. The animal, preferably a rat, is produced by administration of the organism coated with human factor C1q. The organism is, in particular, Neisseria gonorrhoeae. The rat infected with C1q-coated Neisseria gonorrhoeae provides a model for the disease state. This rat model allows the development and testing of possible prophylactic and therapeutic agents for the disease and is particularly useful as a model for the advanced stages of gonococcal infection in females. Prophylactic or therapeutic compositions including antibodies or Neisseria gonorrhoeae peptides with binding specificity for human factor C1q are described. A C1q synthetic analog having binding specificity for N. gonorrhoeae and without binding specificity for eukaryotic cells is described as being useful to treat gonococcal infection. |
priorityDate |
1993-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |