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filingDate 1994-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6f9a994d2fad078d27dee186b41b702
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publicationDate 1996-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0694042-A1
titleOfInvention Inhibitor of vascular endothelial cell growth factor
abstract The vascular endothelial cell growth factor (VEGF) inhibitors of the present invention are naturally occurring or recombinantly engineered soluble forms with or without a C-terminal transmembrane region of the receptor for VEGF, a very selective growth factor for endothelial cells. The soluble forms of the receptors will bind the growth factor with high affinity but do not result in signal transduction. These soluble forms of the receptor bind VEGF and inhibit its function.
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